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Serologic tests give rises in titer with the responsible viruses and others closely related. Virus may be isolated from blood during acute febrile stage. 2. Occurrence — All recognized outbreaks have been in urban areas of Philippine Islands and in Thailand. Major outbreaks in Manila and Bangkok, Arthropod-Borne Viral Hemorrhagic Fevers 35 but smaller urban areas also involved. Occurrence is limited to rainy Not observed where seasons and areas of high A. aegypti prevalence. only Aedes albopictus is present.

4. Terminal disinfection: Thorough cleaning. 5. Quarantine: None. 6. Immunization of 7. Investigation of contacts 8. Specific treatment: None. contacts: and source of infection: Not profitable. No spontaneous recovery. Prolonged administration of sulfonamides, penicillin, chlortetracycline, or chloramphenicol is usually effective; prognosis poor in meningitis. C. Epidemic measures: Not applicable, a sporadic disease. D. International measures: None. AFRICAN TICK-BORNE FEVER, RICKETTSIAL 1. —A moderately severe illness, characterized by an with tender enlarged lymph nodes, a febrile period of about 10 days and a generalized maculopapular erythematous rash which appears about the fourth or fifth day, usually involves palms and soles and persists 6 to 7 days; with antibiotic treatment, fever lasts no more than 2 days.

6. Immunization of 7. Investigation of contacts 8. Specific treatment: None. contacts: and source of infection: Not profitable. No spontaneous recovery. Prolonged administration of sulfonamides, penicillin, chlortetracycline, or chloramphenicol is usually effective; prognosis poor in meningitis. C. Epidemic measures: Not applicable, a sporadic disease. D. International measures: None. AFRICAN TICK-BORNE FEVER, RICKETTSIAL 1. —A moderately severe illness, characterized by an with tender enlarged lymph nodes, a febrile period of about 10 days and a generalized maculopapular erythematous rash which appears about the fourth or fifth day, usually involves palms and soles and persists 6 to 7 days; with antibiotic treatment, fever lasts no more than 2 days.

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Control of communicable diseases in man; an official report by American Public Health Association


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