This useful e-book offers a complete evaluate of the epidemiology and medical presentation of acute coronary syndromes (ACS). It additionally publications the reader via threat evaluate, possibility stratification, analysis, and remedy of ACS.
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Additional info for Acute Coronary Syndromes in Clinical Practice
New guidelines recommend aspirin 162–325 mg/day among patients who receive a coronary stent (3 months for a sirolimus stent and 6 months for a paclitaxel stent), then decrease to 75–162 mg/day [4,6]. The use of ibuprofen is discouraged due to an interaction with aspirin; however, if this medicine is used it should be given at least 8 hours before or 30 minutes after the administration of aspirin . Reproduced with permission from Peters et al. . Anti-platelet Therapies 39 Clopidogrel Clopidogrel is a relatively new cardiovascular agent that acts by irreversibly blocking the platelet adenosine diphosphate (ADP) receptor, thus preventing platelet aggregation.
Among the patients who underwent percutaneous coronary intervention, the use of enoxaparin appeared to be superior to unfractionated heparin . Attention must be given to careful dosing, especially among the elderly and those with diminished renal function. , enoxaparin) is a reasonable alternative to unfractionated heparin for conservatively treated non-ST-elevation ACS and thrombolytic-treated ST-elevation myocardial infarction . Lowmolecular-weight heparin is contraindicated with a heparin allergy and requires cautious use in the elderly and patients with renal insufficiency.
Utilization of early invasive management strategies for high-risk patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE Quality Improvement Initiative. JAMA 2004; 292:2096–2104. 10. , Dabbous OH, et al. Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE). Heart 2007; 93:177–182. 36 Acute Coronary Syndromes in Clinical Practice 11. Lee KL, Woodlief LH, Topol EJ, et al.
Acute Coronary Syndromes in Clinical Practice